AutoFocus: AI-driven alignment of nanofocusing X-ray mirror systems

We describe the application of aan AI-driven system to autonomously align and focus complex x-ray mirror systems . The system has been developed and studied on a digital twin of nanofocusing X-ray beamlines, built using advanced optical simulation tools calibrated with wavefront sensing data collected at the beamline.We experimentally demonstrated that the system is systematically capable of positioning a focused beam on the sample, both by simulating the life cycle of the beamline with random perturbations due to typical variations in the light source and optical elements over time, and by conducting similar tests on an actual focusing system.