posted on 2025-01-22, 07:24authored byXincheng Yao, Tobiloba Adejumo, Taeyoon Son, Guangying Ma, Mojtaba Rahimi, ALBERT DADZIE, Jie Ding
This study verifies anisotropic vessel pulsatility in human retinas. Doppler Optical Coherence Tomography (OCT) was utilized for dynamic monitoring of peripapillary vessel lumen dynamics. Quantitative analysis consistently revealed larger axial compared to lateral lumen changes, with an axial-to-lateral pulsation change ratio of 1.29 ± 0.08. These findings highlight the anisotropic biomechanical properties of retinal tissue, which contribute to direction-dependent vascular dynamics. Quantitative assessment of anisotropic vascular biomechanics offers promising insights for improving the detection of vascular alterations associated with ocular conditions.
History
Funder Name
National Eye Institute (P30 EY001792,R01 EY029673,R01 EY030101,R01 EY030842,R01 EY023522,R44 EY028786); Research to Prevent Blindness; Richard and Loan Hill Department of Biomedical Engineering, University of Illinois at Chicago